This Week in Virology #62: Persistence of West Nile virus

Hosts: Vincent Racaniello, Dickson Despommier, and Alan Dove

On episode #62 of the podcast This Week in Virology, Vincent, Dickson, and Alan discuss STEP HIV-1 vaccine failure caused by the adenovirus vector, presence of West Nile virus in kidneys for years after initial infection, adaptation of the influenza viral RNA polymerase for replication in human cells, and the significance of the D225G change in the influenza HA protein.

Download TWiV #62 (47 MB .mp3, 66 minutes)

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email.

Links for this episode:

• HIV vaccine failure probably caused by adenovirus vector used


• Persistence of West Nile virus in kidneys for years (JID and ProMedMail) (thanks, Lenn!)


• Adaptive strategies of influenza RNA polymerase for replication in humans


• New CDC estimates of 2009 H1N1 infection in US


• Receptor binding specificity of 2009 H1N1 virus


• Distribution of sialic acids in human respiratory tract

Weekly Science Picks
Dick Smallpox - The Death of a Disease by DA Henderson
Alan Olympus Bioscapes Digital Imaging Competition
Vincent Microbe Magazine

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv or leave voicemail at Skype: twivpodcast. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.